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Undergraduate students presenting at CSETAC meeting, Durham, NC

Undergraduate students, Madeline Vera and Diamond Hill, will present posters at the Annual Meeting of the Carolina Chapter of SETAC (Society of Environmental Toxicology and Chemistry) in Durham, NC. The meeting will be held at  Syngenta Crop Protection, LLC. 9 Davis Drive, Durham, NC 27703 on April 25-27, 2018.

Madeline will present transgenerational gene expression differences in the brain of the male medaka fish caused by the past embryonic exposure to birth control pill component, 17 alpha-ethinylestradiol. Diamond will present transgenerational dysregulation of osmoregulation-related genes in the gills of medaka fish caused by the past embryonic exposure to bisphenol A (BPA). The past exposure indicates a direct contact with the stressor three generations ago. Many chemicals that were in the environment once upon a time do not exist anymore, but our studies, including that of others, suggest that the exposure, especially embryonic or parental during reproductively active stages, have far reaching health consequences. These effects can travel across several generations via epigenetic inheritance mechanisms. Therefore, it seems essential for evaluating past exposure effects in the current generation to protect them from the adverse outcomes that may arise over time.

Who wants their grandchildren to pay for the debt that they never borrowed? Do we really have tools to examine their debt.  We run “Transgenerational Credit History” of grandchildren using epigenetic tools to find out if they owe any.


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