Ramji Bhandari

Ramji Bhandari

Assistant Professor
Bernard-Glickman Dean's Professor

(336) 256-0493
405 Eberhart Building


Gene Environment Interactions and Epigenetics


Ph.D., Hokkaido University


My research interests are to elucidate mechanisms underlying gene environment interactions and developmental origins of adult and transgenerational health abnormalities. My group takes comparative, molecular, cellular, and bioinformatics analysis approaches and utilizes cell/tissue culture and animal models (fish and rodents). Current projects include basic science of germ cell epigenetic programming, epigenotoxicity of environmental stressors such as: pharmaceuticals, pesticides, bisphenol A, marijuana (including its metabolites), engineered nanoparticles, etc., and trangenerational inheritance of  epimutations.


Recent Publications:

Wang X., Bhandari R.K. (2019). The dynamics of DNA methylation during epigenetic reprogramming of primordial germ cells in medaka (Oryzias latipes). Epigenetics. doi: 10.1080/15592294.2019.1695341. [PMID: 31851575]

Khanal, S., Bhattarai, S.R., Sarkar, J., Bhandari, R.K., McDonald, J., Bhattarai, N.P. (2019). Nano-fiber integrated microcapsules: A nano-in-micro platform for 3D cell culture. Scientific Reports. [PMID: 31562351]

Wang. X., Bhandari. R.K. (2019). DNA methylation dynamics during epigenetic reprogramming of medaka embryo. Epigenetics. 1-10. [PMID: 31010368]

Wang, X., Hill, D., Tillitt, D.E., Bhandari, R.K. (2019). Bisphenol A and 17alpha-ethinylestradiol induced transgenerational differences in expression of osmoregulatory genes in the gill of medaka (Oryzias latipes). Aquatic Toxicology. 211: 227-234. [PMID: 31048106]

Cleary, J.C., Tillitt, D.E., vom Saal, F.S., Nicks, D.K., Claunch, R.A, Bhandari, R.K. (2019). Transgenerational effects of developmental Atrazine exposure on reproductive axis of medaka. Environmental Pollution, 251: 631-650. [PMID: 31108297]

Smith, C.S., Vera, M.K.M., Bhandari, R.K. (2019). Developmental and epigenetic effects of Roundup and glyphosate exposure on medaka (Oryzias latipes). Aquatic Toxicology, 210:215-226. [PMID: 30875550]

Bhandari, R.K., Taylor J.A., Sommerfield-Sager J., Tillitt D.E., Ricke W.A., Vom Saal F.S. (2019). Estrogen receptor 1 expression and methylation of Esr1 promoter in mouse fetal prostate mesenchymal cells induced by gestational exposure to bisphenol A or ethinylestradiol. Environmental Epigenetics. 5:dvz012 doi: 10.1093/eep/dvz012 [PMID: 31463084]

Complete list of publications in google scholar


Developmental Biology (BIO 464)
Molecular Approaches to Research: Transgenerational Inheritance (Bio 596)
Human Embryology and Teratology (Bio 614)