Evolution and dynamics of microbial communities
Ph.D., Institute Pasteur, Paris, France
As an evolutionary biologist, my broad interest is in understanding how microbes evolve and adapt as populations and communities. My research has addressed microbial evolution both at the broad-scale (e.g. ancient evolutionary relationships) and fine-scale (e.g. microbial community response to perturbation). Currently, my lab uses the honeybee, an important agricultural and environmental pollinator, as a model system to study the evolution and dynamics of host-associated microbial communities. In particular, we are interested in understanding how chemical and environmental perturbations impact the population dynamics of the honeybee gut microbial communities and how these perturbations impact honeybee health. It is well known that perturbed communities can lead to infection by several pathogens, including opportunists, but the processes of how perturbation facilitates invasion remain elusive. Our research involves investigating how microbial community imbalance and within-host evolution influences pathogen susceptibility, what role resident microbes play in protecting their host, and how and when opportunistic pathogens become virulent.
Recent Grant Awards:
2016–2018: USDA AFRI Food, Agriculture, Natural Resources, and Human Sciences Education and Literacy Initiative (ELI) Postdoctoral Fellowship
Raymann K, Coon K, Shaffer Z, Moran NA. 2018. Pathogenicity of Serratia marcescens strains in honey bees. mBio. 9:e01649-18.
Motta EVS, Raymann K, Moran NA. 2018. Glyphosate perturbs the gut microbiota of honey bees. Proc Natl Acad Sci USA. 115:10305-10310.
Raymann K*, Motta EVS*, Girard C*, Riddington IM, Dinser JA, Moran NA. 2018. Imidacloprid decreases honey bee survival but does not affect the gut microbiome. Appl Environ Microbiol. doi: 10.1128/AEM.00545-18.
Raymann K and Moran NA. 2018. The role of the gut microbiome in health and disease of adult workers. Curr Opin Insect Sci. 26:97-104.
Raymann K, Bobay LM, Moran NA. 2017. Antibiotics reduce genetic diversity of core species in the honeybee gut microbiome. Mol Ecol. doi: 10.1111/mec.14434.
Raymann K, Shaffer Z, Moran NA. 2017. Antibiotic exposure perturbs the gut microbiota and elevates mortality in honeybees. PLoS Biol. 15:e2001861
Raymann K, Moeller A, Goodman, A, Ochman H. 2017. Unexplored archaeal diversity in the great ape gut microbiome. mSphere. 2:e00026-17
Raymann K, Brochier-Armanet C, and Gribaldo S. 2015. The two-domain tree of life is linked to a new root for the Archaea. Proc Natl Acad Sci USA. 112:6670–6675
Raymann K, Forterre P, Brochier-Armanet C, Gribaldo S. 2014. Global phylogenomic analysis disentangles the complex evolutionary history of DNA replication in Archaea. Genome Biol Evol. 6:192–212
Probst A, Weinmaier T, Raymann K, Perras A, Gribaldo S, Rattei T, Banfield JF, Moissl-Eichinger C. 2014. Biology of a widespread uncultivated archaeon that contributes to
carbon fixation in the subsurface. Nat Commun. 5:5497
Forterre P, Krupovic M, Raymann K, Mayer C, Gadelle D. 2014. DNA topoisomerase VIII: a novel family of Topo IIB encoded by free or integrated plasmids in Archaea and Bacteria. Nucleic Acids Res. 42:8578–8591
Borrel G, Parisot N, Harris HMB, Peyretaillade E, Gaci N, Tottey W, Bardot O, Raymann K, Gribaldo S, Peyret P, O’Toole PW, Brugère JF. 2014. Comparative genomics highlights the unique biology and diversity of a Thermoplasmata-related seventh order of methanogenic archaea that encodes pyrrolysine. BMC Genomics. 15:679
Raymann K, Bobay LM, Doak TG, Lynch M, Gribaldo, S. 2013. A genomic survey of Reb homologs suggests widespread occurrence of r-bodies in Proteobacteria. G3 (Bethesda). 3:505–516
General Microbiology (BIO 481)
Internships in Biology (BIO 497)
Symbiosis (BIO 560)