Germ Cell Development

Epigenetic mechanisms underlying germ cell development

Sex differences in germ cells are believed to be epigenetically regulated, as distinct differences in DNA methylation and histone modifications have been found in germ cells during sex determination. We are studying epigenetic regulation of germ cell development, including the process of epigenetic reprogramming of primordial germ cells (PGCs), by using olvasGFP medaka as a model organism.

Medaka fry (female, 3 days post hatch) with GFP in germ cells

Adult testis with GFP in germ cells

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