Germ Cell Development
Epigenetic mechanisms underlying germ cell development
We are studying epigenetic regulation of germ cell development in medaka gonads by using vasa-gfp medaka as a model. Sex differences in germ cells are believed to be epigenetically regulated, as distinct differences in DNA methylation and histone modifications have been found in germ cells during sex determination. We dissect epigenetic landscape of germ cells at various stages of development.