Germ Cell Development

Epigenetic mechanisms underlying germ cell development

We are studying epigenetic regulation of germ cell development in medaka gonads by using vasa-gfp medaka as a model. Sex differences in germ cells are believed to be epigenetically regulated, as distinct differences in DNA methylation and histone modifications have been found in germ cells during sex determination. We dissect epigenetic landscape of germ cells at various stages of development.

Medaka fry (female, 3 days post hatch) with GFP in germ cells

Adult testis with GFP in germ cells

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