Epigenetic Effects of Early Developmental Exposure to Emerging Environmental Contaminants
A growing number of studies reveal the fact that the aquatic environment is threatened by an increasing rate of chemical contamination. As a result, aquatic fauna is impacted by the ubiquitous presence of these chemicals in water bodies. Our research suggests that developmentally established epigenetic changes can survive in the body throughout the lifetime of the exposed individual and are associated with adverse health effects later in life. We aim to develop an adverse outcome pathway (AOP) incorporating epigenetic effects and associated phenotypic traits using medaka fish as an animal model. In the near future, regulatory agencies will need scientific information to classify chemicals that are transgenerationally harmful to humans and the ecosystem.
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