Dr. Xuegeng Wang

Dr. Xuegeng Wang
Postdoctoral Fellow

Contact
x_wang24@uncg.edu
336-450-8854
361 Eberhart Building

Education
Ph.D. (2017). Peking University

Research
Environmental stressors can establish epigenetic memories in the primordial germ cells that are precursors of eggs and sperm. Environmentally established epigenetic memories may escape epigenetic reprogramming during early embryogenesis and sex determination and maintain permanent profile leading to various reproductive and non-reproductive diseases in the offspring across several generations. My research focus is to dissect phenotypes and their genomewide epigenetic association in medaka fish exposed to environmental stressors.


Recent Publications

  1. Lan Jiang, Jing Zhang, Jing-Jing Wang, Lu Wang, Li Zhang, Guoqiang Li, Xiaodan Yang, Xin Ma, Xin Sun, Jun Cai, Jun Zhang, Xingxu Huang, Miao Yu, Xuegeng Wang, Feng Liu, Chung-I Wu, Chuan He, Bo Zhang, Weimin Ci, Jiang Liu. 2013. Sperm, but Not Oocyte, DNA methylome is inherited by zebrafish early embryos. Cell, 153:773-784.
  2. Xuegeng Wang, Zuoyan Zhu, Yonghua Sun, Jue Zhao. 2013. Nuclear transfer and reprogramming in fish. Hereditas (Beijing), 35(4), 433-440. (Review)
  3. Xuegeng Wang*, Yi Zhao*, Tian Tian, Zuoyan Zhu, Jingchu Luo, Jue Zhao. Genome-wide DNA methylation analysis of somatic cell nuclear transfer (SCNT) zebrafish embryos. (In preparation, *co-first author).
  4. Yi Zhao*, Xuegeng Wang*, Zuoyan Zhu, Jingchu Luo, Jue Zhao. The DNA methylation landscape of zebrafish embryos during blastula-gastrulation transition. (In preparation, *co-first author).