Vincent C. Henrich, Professor | UNCG Biology

Vincent C. Henrich, Professor

Vincent C. HenrichResearch:

My current research is focused on (1) understanding the genetic basis for a variety of life-limiting human clinical conditions through genetic association studies, (2) developing technological tools for more sensitive and precise measurement of biologically relevant molecules for both research and clinical applications, and (3) evaluating the use of family health history and genetics to identify patients with an elevated risk for diseases such as cancer and diabetes, with a focus on disease prevention.

The research is being conducted in collaboration with faculty members at UNCG, the Joint School of Nanosciences and Nanoengineering (JSNN), and Duke University. Our recent efforts have led to the identification of specific single nucleotide polymorphisms (SNPs) in the human genome associated with susceptibility to noise-induced hearing loss in young adults and with susceptibility to noncontact knee injuries in young female athletes. We have also initiated studies to evaluate various genetic variants for their effects on maternal-infant bonding and recovery from traumatic brain injury, as well as the effects of exercise on cognition in individuals who are genetically susceptible to Alzheimer's disease. For all of these conditions, we are particularly interested in the interplay of environmental factors and genetic variation as they affect human conditions. We are also working with faculty members at the JSNN to develop tools with improved sensitivity and specificity for detecting DNA, RNA, and biomarker proteins for both research and clinical purposes. Interestingly, some of these variants involve the genes that encode nuclear receptors, an area of research focus which has continued in my laboratory for many years.

Recent Publications:

Buchanan, AH, CA Christianson, T Himmel, KP Powell, A Agbaje, GS Ginsburg, VC Henrich, and LA Orlando. (2014). Use of a patient-centered family health history tool with decision support in primary care: Impact of identification of increased risk patients on genetic counseling attendance. DOI 10.1007/s10897-014-9753-0

Beadles, CA, R R Wu, T Himmel, AH Buchanan, KP Powell, E Hauser, VC Henrich, GS Ginsburg, and LA Orlando. (2014). Providing patient education: impact on quality and quantity of family health history collection. Familial Cancer doi:10.1007/s10689-014-9701-z

R Ryanne Wu, TL Himmel, AH Buchanan, KP Powell, ER Hauser, GS Ginsburg, VC Henrich, and LA Orlando. (2014). Quality of family history collection with use of a patient facing family history assessment tool. BMC Family Practice 15, 31.

R Ryanne Wu, LA Orlando, T L Himmel, AH Buchanan, KP Powell, ER Hauser, AB Agbaje, VC Henrich and GS Ginsburg. (2013). Patient and primary care provider experience using a family health history collection, risk stratification, and clinical decision support tool: A Type 2 hybrid controlled implementation-effectiveness trial. BMC Family Practice
MS : 8777186999150797

Orlando, LA, AH Buchanan, SE Hahn, CA Christianson, KP Powell, CS Skinner, B Chesnut, C Blach, B Due, GS Ginsburg, VC Henrich. (2013). Development and validity of a primary care based family health history and decision-support program: MeTree© NC Med. J., 74, 287-296.

Orlando, LA, VC Henrich, ER Hauser, C Wilson, and GS Ginsburg, for the Genomedical Connection. (2013). The genomic medicine model: an integrated approach to implementation of family health history in primary care. Personalized Medicine, 10, 295-306.

K.P. Powell, CA Christianson, S E Hahn, G Dave, LR Evans, SH Blanton, E Hauser, A Agbaje, L A Orlando, G S. Ginsburg, VC Henrich, and The Genomedical Connection. (2013). Collection of Family Health History for Chronic Diseases in Primary Care. NC Medical Journal, 74(4):279-86 .

G. Jones, P. Teal; V. Henrich; A. Krzywonos, A. Sapa, M. Wozniak, J. Smolka, and D Jones. (2013). Ligand Binding Pocket Function of Drosophila USP is Necessary for Metamorphosis. Gen. Comp. Endocrinol., 182:73-82.

Bell, RD, SJ Shultz, L Wideman and VC Henrich. (2012). Collagen gene variants previously associated with anterior cruciate ligament injury risk are also associated with joint laxity. J. Sports Health, 4, 312-318.

Christianson, CA, Powell KP, Hahn, SE, Blanton, SH, Bogacik, J, VC Henrich and the Genomedical Connection. (2012). The use of a family history risk assessment tool within a community health care system: Views of primary care providers. J Genet. Counsel, DOI 10.1007/s10897-011-9479-1.

Classes:

Genetics (BIO 392)
Genetics Lab (BIO 393)
Undergraduate Research (BIO 499)

Contact:

211 Eberhart Building
(336)334-4775

E-mail